Model Number

127-07-1

Hydroxyurea
Molecular formula:CH4N2O2
CAS:127-07-1
Hydroxyurea is used for the following indications:

Myeloproliferative disease (primarily polycythemia vera not responding to blood-letting[citation needed] and essential thrombocytosi
Sickle-cell disease[5] (breaks down cells that are prone to sickle, as well as increasing fetal hemoglobin content)
AIDS as an adjunct to ddI in combination antiretroviral therapies[6]
Second line treatment for psoriasis[7] (slows down the rapid division of skin cells)
Biochemical research as a DNA replication inhibitor[8] that causes deoxyribonucleotide depletion and results in DNA double strand breaks near replication forks